WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_TTGTTT_V$FOXO4_01       ID:DB_ID:2416
C=2037; O=12; E=2.98; R=4.03; rawP=3.38e-05; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163516 NA ANKZF1 ankyrin repeat and zinc finger domain containing 1 55139 ENSG00000163516
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000104946 NA TBC1D17 TBC1 domain family, member 17 79735 ENSG00000104946
4  ENSG00000164338 NA UTP15 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) 84135 ENSG00000164338
5  ENSG00000198060 NA MARCH5 membrane-associated ring finger (C3HC4) 5 54708 ENSG00000198060
6  ENSG00000185920 NA PTCH1 patched 1 5727 ENSG00000185920
7  ENSG00000178074 NA C2orf69 chromosome 2 open reading frame 69 205327 ENSG00000178074
8  ENSG00000108799 NA EZH1 enhancer of zeste homolog 1 (Drosophila) 2145 ENSG00000108799
9  ENSG00000100100 NA PIK3IP1 phosphoinositide-3-kinase interacting protein 1 113791 ENSG00000100100
10  ENSG00000153094 NA BCL2L11 BCL2-like 11 (apoptosis facilitator) 10018 ENSG00000153094
11  ENSG00000141699 NA FAM134C family with sequence similarity 134, member C 162427 ENSG00000141699
12  ENSG00000198900 NA TOP1 topoisomerase (DNA) I 7150 ENSG00000198900


Database:Transcription Target       Name:hsa_V$FOXO1_02       ID:DB_ID:2129
C=238; O=5; E=0.35; R=14.38; rawP=2.66e-05; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185920 NA PTCH1 patched 1 5727 ENSG00000185920
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000104946 NA TBC1D17 TBC1 domain family, member 17 79735 ENSG00000104946
4  ENSG00000100100 NA PIK3IP1 phosphoinositide-3-kinase interacting protein 1 113791 ENSG00000100100
5  ENSG00000108799 NA EZH1 enhancer of zeste homolog 1 (Drosophila) 2145 ENSG00000108799


Database:Transcription Target       Name:hsa_V$FOXO3_01       ID:DB_ID:2131
C=243; O=5; E=0.35; R=14.09; rawP=2.93e-05; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185920 NA PTCH1 patched 1 5727 ENSG00000185920
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000114626 NA ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 80325 ENSG00000114626
4  ENSG00000104946 NA TBC1D17 TBC1 domain family, member 17 79735 ENSG00000104946
5  ENSG00000108799 NA EZH1 enhancer of zeste homolog 1 (Drosophila) 2145 ENSG00000108799


Database:Transcription Target       Name:hsa_CACGTG_V$MYC_Q2       ID:DB_ID:2434
C=1015; O=9; E=1.48; R=6.07; rawP=1.62e-05; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000104356 NA POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 10940 ENSG00000104356
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000107651 NA SEC23IP SEC23 interacting protein 11196 ENSG00000107651
4  ENSG00000170271 NA C5orf4 chromosome 5 open reading frame 4 10826 ENSG00000170271
5  ENSG00000100105 NA PATZ1 POZ (BTB) and AT hook containing zinc finger 1 23598 ENSG00000100105
6  ENSG00000185920 NA PTCH1 patched 1 5727 ENSG00000185920
7  ENSG00000100100 NA PIK3IP1 phosphoinositide-3-kinase interacting protein 1 113791 ENSG00000100100
8  ENSG00000149150 NA SLC43A1 solute carrier family 43, member 1 8501 ENSG00000149150
9  ENSG00000198900 NA TOP1 topoisomerase (DNA) I 7150 ENSG00000198900


Database:Transcription Target       Name:hsa_V$FOXO4_02       ID:DB_ID:2130
C=253; O=5; E=0.37; R=13.53; rawP=3.56e-05; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185920 NA PTCH1 patched 1 5727 ENSG00000185920
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000104946 NA TBC1D17 TBC1 domain family, member 17 79735 ENSG00000104946
4  ENSG00000100100 NA PIK3IP1 phosphoinositide-3-kinase interacting protein 1 113791 ENSG00000100100
5  ENSG00000108799 NA EZH1 enhancer of zeste homolog 1 (Drosophila) 2145 ENSG00000108799


Database:Transcription Target       Name:hsa_V$YY1_02       ID:DB_ID:1886
C=239; O=5; E=0.35; R=14.32; rawP=2.71e-05; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000164163 NA ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 6059 ENSG00000164163
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000104946 NA TBC1D17 TBC1 domain family, member 17 79735 ENSG00000104946
4  ENSG00000100105 NA PATZ1 POZ (BTB) and AT hook containing zinc finger 1 23598 ENSG00000100105
5  ENSG00000109606 NA DHX15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 1665 ENSG00000109606


Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=14; E=4.22; R=3.32; rawP=5.89e-05; adjP=0.0015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000137497 NA NUMA1 nuclear mitotic apparatus protein 1 4926 ENSG00000137497
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000114626 NA ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 80325 ENSG00000114626
4  ENSG00000136868 NA SLC31A1 solute carrier family 31 (copper transporters), member 1 1317 ENSG00000136868
5  ENSG00000104946 NA TBC1D17 TBC1 domain family, member 17 79735 ENSG00000104946
6  ENSG00000112972 NA HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 3157 ENSG00000112972
7  ENSG00000101367 NA MAPRE1 microtubule-associated protein, RP/EB family, member 1 22919 ENSG00000101367
8  ENSG00000100105 NA PATZ1 POZ (BTB) and AT hook containing zinc finger 1 23598 ENSG00000100105
9  ENSG00000069956 NA MAPK6 mitogen-activated protein kinase 6 5597 ENSG00000069956
10  ENSG00000185920 NA PTCH1 patched 1 5727 ENSG00000185920
11  ENSG00000078140 NA UBE2K ubiquitin-conjugating enzyme E2K 3093 ENSG00000078140
12  ENSG00000106080 NA FKBP14 FK506 binding protein 14, 22 kDa 55033 ENSG00000106080
13  ENSG00000149150 NA SLC43A1 solute carrier family 43, member 1 8501 ENSG00000149150
14  ENSG00000198900 NA TOP1 topoisomerase (DNA) I 7150 ENSG00000198900


Database:Transcription Target       Name:hsa_TGCGCANK_UNKNOWN       ID:DB_ID:2366
C=537; O=6; E=0.78; R=7.65; rawP=0.0001; adjP=0.0023
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000183155 NA RABIF RAB interacting factor 5877 ENSG00000183155
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000107651 NA SEC23IP SEC23 interacting protein 11196 ENSG00000107651
4  ENSG00000146223 NA RPL7L1 ribosomal protein L7-like 1 285855 ENSG00000146223
5  ENSG00000078140 NA UBE2K ubiquitin-conjugating enzyme E2K 3093 ENSG00000078140
6  ENSG00000141699 NA FAM134C family with sequence similarity 134, member C 162427 ENSG00000141699


Database:Transcription Target       Name:hsa_RYTGCNNRGNAAC_V$MIF1_01       ID:DB_ID:2433
C=84; O=3; E=0.12; R=24.45; rawP=0.0003; adjP=0.0060
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185920 NA PTCH1 patched 1 5727 ENSG00000185920
2  ENSG00000100100 NA PIK3IP1 phosphoinositide-3-kinase interacting protein 1 113791 ENSG00000100100
3  ENSG00000112972 NA HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 3157 ENSG00000112972


Database:Transcription Target       Name:hsa_RTAAACA_V$FREAC2_01       ID:DB_ID:2417
C=907; O=7; E=1.32; R=5.28; rawP=0.0004; adjP=0.0072
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000185920 NA PTCH1 patched 1 5727 ENSG00000185920
2  ENSG00000090447 NA TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 7023 ENSG00000090447
3  ENSG00000114626 NA ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 80325 ENSG00000114626
4  ENSG00000104946 NA TBC1D17 TBC1 domain family, member 17 79735 ENSG00000104946
5  ENSG00000100100 NA PIK3IP1 phosphoinositide-3-kinase interacting protein 1 113791 ENSG00000100100
6  ENSG00000108799 NA EZH1 enhancer of zeste homolog 1 (Drosophila) 2145 ENSG00000108799
7  ENSG00000198060 NA MARCH5 membrane-associated ring finger (C3HC4) 5 54708 ENSG00000198060




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).